Smirnova E
Smirnova
Elena Yu.
PhD
OrcID: 0000-0002-9518-5022
ResearcherID: E-4209-2014
Research Gate: Elena_Smirnova9
Scopus ID: 56810562600
eLibrary ID: 731466
E-Mail: elena.smirnova@mail.ioffe.ru
The domain of neuronal spiking activity in space of control parameters has been built. The model of color and orientation processing in V1 has been developed . 2. Biological closed-loop system has been developed for optogenetic experiment. 3. The mechanism of the antiepileptic effect of thd low-frequency electrical stimulation in the model of epileptiform activity in vitro has been studied. 4. The effect of the low-frequency optogenetic stimulation in the model of epileptiform activity had been studied.
Articles
Smirnova E, Ergina Yu, Zaitsev A / Interneuron-Driven Ictogenesis in the 4-Aminopyridine Model: Depolarization Block and Potassium Accumulation Initiate Seizure-like Activity / Int. J. Mol. Sci. 2025 26(14) : 6812
DOIPubMed
DOIPubMed
Nikitin E.V., Postnikova T, Proskurina E, Borodinova A.A., Ivanova V., Roshchin M., Smirnova E, Kelmanson I., Belousov V., Balaban P., Zaitsev A / Overexpression of KCNN4 channels in principal neurons produces an anti-seizure effect without reducing their coding ability / Gene Ther. 2024 31(3-4) : 144-153
DOI
DOI
Smirnova E, Чижов А. В., Zaitsev A / Optogenetic Low-Frequency Stimulation of Principal Neurons, but Not Parvalbumin-Positive Interneurons, Prevents Generation of Ictal Discharges in Rodent Entorhinal Cortex in an In Vitro 4-Aminopyridine Model / Int J Mol Sci 2022 24(1) : 195
DOIPubMed
DOIPubMed
Чижов А. В., Amakhin D, Smirnova E, Zaitsev A / Ictal wavefront propagation in slices and simulations with conductance-based refractory density model / PLoS Comput Biol. 2022 18(1) : e1009782
DOI
DOI
Smirnova E, Чижов А. В., Zaitsev A / Presynaptic GABAB receptors underlie the antiepileptic effect of low-frequency electrical stimulation in the 4-aminopyridine model of epilepsy in brain slices of young rats / Brain Stimul 2020 13(5) : 1387-1395
DOI
DOI
Чижов А. В., Ekimova I, Smirnova E / Direction selectivity model based on lagged and nonlagged neurons / Advances in Neural Computation, Machine Learning, and Cognitive Research III 2020 V856 : 165-171
DOI
DOI
Smirnova E, Zaitsev A / Use of Optogenetic Methods to Study and Suppress Epileptic Activity (review) / Neuroscience and Behavioral Physiology 2019 49 : 1083–1088
DOI
DOI
Чижов А. В., Zefirov A, Amakhin D, Smirnova E, Zaitsev A / Minimal model of interictal and ictal discharges «Epileptor-2» / PLoS Comput Biol 2018 14(5) : e1006186
DOI
DOI
Smirnova E, Amakhin D, Malkin S, Чижов А. В., Zaitsev A / Acute Changes in Electrophysiological Properties of Cortical Regular-Spiking Cells Following Seizures in a Rat Lithium-Pilocarpine Model / Neuroscience 2018 379 : 202-215
DOI
DOI
Smirnova E, Zaitsev A, Kim K, Чижов А. В. / The domain of neuronal firing on a plane of input current and conductance / J Comput Neurosci. 2015 39(2) : 217-33
DOIPubMed
DOIPubMed
Smirnova E, Chizhkova E, Чижов А. В. / A Mathematical Model of Color and Orientation Processing in V1 / Biol Cybern. 2015 109(4-5) : 537-47
DOIPubMed
DOIPubMed
