Malkin S
Malkin
Sergey L.
к.б.н.
OrcID: 0000-0001-9105-6832
ResearcherID: D-1629-2017
Research Gate: Sergey_Malkin
Scopus ID: 26642547800
eLibrary ID: 914071
E-Mail: adresatt@gmail.com
The main area of my scientific interest is synaptic transmission, and the changes that it undergoes in the process of epileptogenesis, with the focus on the changes that occur in the glutamatergic transmission in hippocampus and neocortex in rat models of epilepsy, and in the epileptic tissue of patients with refractory temporal lobe epilepsy. The main technique is patch-clamp electrophysiology in acute brain slices.
Articles
Malkin S, Zaitsev A / Enhanced excitability of CA1 pyramidal neurons during the latent phase of the Rat lithium-pilocarpine model of temporal lobe epilepsy / Neuroscience 2025 686() : 1551
DOIPubMed
DOIPubMed
Malkin S, Amakhin D, Soboleva E, Postnikova T, Zaitsev A / Synaptic Dysregulation Drives Hyperexcitability in Pyramidal Neurons Surrounding Freeze-Induced Neocortical Malformations in Rats / Int J Mol Sci 2025 9(4) : 1423
DOIPubMed
DOIPubMed
Griflyuk A, Postnikova T, Malkin S, Zaitsev A / Alterations in Rat Hippocampal Glutamatergic System Properties after Prolonged Febrile Seizures / Int J Mol Sci 2023 24(23) : 16875
DOIPubMed
DOIPubMed
Postnikova T, Malkin S, Zakharova M, Smolensky I, Zubareva O, Zaitsev A / Ceftriaxone Treatment Weakens Long-Term Synaptic Potentiation in the Hippocampus of Young Rats / International Journal of Molecular Sciences 2021 22(16) : 8417
DOI
DOI
Zaitsev A, Malkin S, Postnikova T, Smolensky I, Zubareva O, Romanova I, Zakharova M, Karyakin V, Zavyalov V / Ceftriaxone Treatment Affects EAAT2 Expression and Glutamatergic Neurotransmission and Exerts a Weak Anticonvulsant Effect in Young Rats / Int J Mol Sci. 2019 20(23) : 5852
DOI
DOI
Amakhin D, Soboleva E, Ergina Yu, Malkin S, Чижов А. В., Zaitsev A / Seizure-Induced Potentiation of AMPA Receptor-Mediated Synaptic Transmission in the Entorhinal Cortex / Front. Cell. Neurosci. 2018 12 : 486
DOI
DOI
Smirnova E, Amakhin D, Malkin S, Чижов А. В., Zaitsev A / Acute Changes in Electrophysiological Properties of Cortical Regular-Spiking Cells Following Seizures in a Rat Lithium-Pilocarpine Model / Neuroscience 2018 379 : 202-215
DOI
DOI
Amakhin D, Malkin S, Ergina Yu, Kryukov K, Veniaminova E, Zubareva O, Zaitsev A / Alterations in Properties of Glutamatergic Transmission in the Temporal Cortex and Hippocampus Following Pilocarpine-Induced Acute Seizures in Wistar Rats / Front Cell Neurosci 2017 11 : 264
DOI
DOI
Malkin S, Amakhin D, Veniaminova E, Kim K, Zubareva O, Magazanik L, Zaitsev A / Changes of AMPA receptor properties in the neocortex and hippocampus following pilocarpine-induced status epilepticus in rats / Neuroscience 2016 327 : 146–155
DOI
DOI
Malkin S, Kim K, Tikhonov D, Magazanik L, Zaitsev A / Statistical models suggest presence of two distinct subpopulations of miniature EPSCs in fast-spiking interneurons of rat prefrontal cortex / Neuroscience 2015 301 : 508–519
DOI
DOI
