Over the previous five years, the Laboratory of Functional Biochemistry of Muscles (No. 18) investigated the topic of “Physiological mechanisms of adaptation of muscle effectors of the cardiovascular system to extreme and stressful conditions (i.e., ischemia, hypoxia, toxic inorganic cations, etc.) Laboratory´s staff carried out research and published its results—about 50 articles and abstracts since […]
mitochondria
Shemarova I
For many years, I. V. Shemarova studied the mechanisms of intracellular signaling; she developed biological models for studying the toxic and inhibitory effects of biologically active substances and xenobiotics; studied the influence of Ca2+ and some metals on the proliferation of model organisms. Together with colleagues (S. M.Korotkov, K. V.Sobol, V. P. Nesterov), Shemarova I. […]
Korotkov S
Sergey Korotkov researches the effects of heavy metals (Tl+, Cd2+), as well as Y3+, lanthanides (La3+, Pr3+, Nd3+, Gd3+) and some xenobiotics (diazoxide, pinacidil) on the properties of isolated rat and heart mitochondria. Oxygen consumption rate (respiration) is studied in experiments with energized mitochondria being in various energetic states of 4, 3, and 3UDNP (uncoupled […]
Stepanov A
Research interests include the investigation of structural and functional changes of myocardium in various pathological conditions (chronic heart failure, diabetic cardiomyopathy, etc.).
