Shemarova I

Shemarova I

Shemarova

Irina V.

PhD

ResearcherID:  AAM-7376-2020
Research Gate:  Irina_Shemarova
Scopus ID:  6603363622
E-Mail:  shem@iephb.ru

For many years, I. V. Shemarova studied the mechanisms of intracellular signaling; she developed biological models for studying the toxic and inhibitory effects of biologically active substances and xenobiotics; studied the influence of Ca2+ and some metals on the proliferation of model organisms. Together with colleagues (S. M.Korotkov, K. V.Sobol, V. P. Nesterov), Shemarova I. V. investigated the mechanisms of action of a number of poorly studied metals on the myocardium. It was found that differences in the effect of the metals on myocardial contraction are due to their competitive influence on voltage-gated Ca2+ channels and selective action on the inner membrane of mitochondria (Cd2+ > Ni2+> La3+ > Y3+> Pr3+>Nd3+). The obtained data are important for understanding the influence of the studied metals on the human cardiovascular system.

Articles

Korotkov S, Sobol K, Shemarova I, Novozhilov A, Nikitina E, Nesterov V / Effects of Gd3+ and Ca2+ on Frog Heart Muscle Contractility and Respiration, Swelling and Inner Membrane Potential of Rat Heart Mitochondria / Journal of Evolutionary Biochemistry and Physiology 2020 56 : 541–549
DOI
Nesterov V, Burdygin A, Nesterov S, Ivanov K, Korotkov S, Sobol K, Shemarova I / Pecularities of Cardiohemodynamics and its Autonomic Regulation in Elderly People / J Evol Biochem Phys 2019 55(6) : 483-492
DOI
Korotkov S, Sobol K, Shemarova I, Furaev V, Novozhilov A, Nesterov V / Effects of Nd3+ on Calcium-Dependent Processes in Isolated Rat Heart Mitochondria and Frog Heart Muscle / Biochemistry (Moscow), Supplement Series A: Membrane and Cell Biology 2019 13 : 161–167
DOI