Rukoyatkina N

Rukoyatkina N

Rukoyatkina

Natalia I.

PhD

OrcID:  0000-0002-3920-206X
ResearcherID:  AAN-2227-2020
Research Gate:  Natalia_Rukoyatkina
Scopus ID:  6506507726
eLibrary ID:  97937
E-Mail:  natalia.rukoyatkina@gmail.com

Natalia Rukoyatkina earned her PhD (Physiology) from Sechenov Institute of Evolutionary Physiology and Biochemistry RAS in 1987. In 1995 she joined Laboratory of Behavioral Science of Gerontology in Baltimore (USA). After a couple of years, she moved to Germany to join the Division of Nephrology and then Institute of Clinical Biochemistry and Pathobiochemistry of University of Wuerzburg (till 2014). Main domain of Natalia Rukoyatkina scientific work involves investigations of mechanisms of platelet inhibitions and platelet death induced by different anticancer drugs (inhibitors of BCL-2 protein, lipoxygenase, PLC and drug of natural origins such as curcumin, nobiletin and others). She participates in a number of RFBR grants (contests: A, KOMFI), supervises the scientific work of SPBU students. In her research work she uses Western blotting, laser diffraction and flow cytometry methods.

Articles

Rukoyatkina N, Sokolova T, Pronin N, Andrei Whaley, Anastasiia OWhaley, Gambaryan S / Death of Leukemia Cells and Platelets Induced by 3,3′-Dihydroxy-4,5-Dimethoxybibenzyl Is Mediated by p38 Mitogen-Activated Protein Kinase Pathway / Molecules 2025 30(14) : 2965
DOIPubMed
Pronin N, Whaley AK, Whaley AO, Kuzmina SA, Rukoyatkina N, Gambaryan S / ISOLATION OF SECONDARY METABOLITES OF Rhaponticum carthamoides (WILLD.) ILJIN AND ASSESSMENT OF THEIR ANTIPLATELET ACTIVITY / Pharm Chem J+ 2025 59(3) : 324-329
DOIeLibrary
Fock E, Pronin N, Rukoyatkina N, Whaley A, Gambaryan S, Whaley A. / Thrombin-induced platelet inhibition by 2',4'-dihydroxychalcone and 2',4'-dihydroxydihydrochalcone is mediated by inhibition of ROS production and Thromboxane synthase a activity: structure-activity relationship of polyphenol secondary metabolites from Empetrum nigrum / Nat Prod Res. 2025 39(12) : 3382-3390
DOIwww
Rukoyatkina N, Mindukshev I, Mikhailova D, Panteleev MA, Gambaryan S / Multifaceted effects of thymoquinone on platelet calcium homeostasis / Cells 2025 14(22) : 1827
DOIPubMed
Fock E, Pronin N, Rukoyatkina N, Whaley A, Gambaryan S, Whaley A / Thrombin-induced platelet inhibition by 2',4'-dihydroxychalcone and 2',4'-dihydroxydihydrochalcone is mediated by inhibition of ROS production and Thromboxane synthase a activity: structure-activity relationship of polyphenol secondary metabolites from Empetrum nigrum. / A.Nat Prod Res. 2024 3 : 1-9
DOIPubMed
Shpakova V, Rukoyatkina N, Walter U, Gambaryan S / Potential and limitations of PKA/ PKG inhibitors for platelet studies / Platelets 2021 33(6) : 1-10
DOI
Rukoyatkina N, Shpakova V, Bogoutdinova A, Kharazova A, Mindukshev I, Gambaryan S / Curcumin by activation of adenosine A2A receptor stimulates protein kinase A and potentiates inhibitory effect of cangrelor on platelets / Biochemical and Biophysical Research Communications 2021 586(2022) : 20-24
DOI
Rukoyatkina N, Shpakova V, Sudnitsyna J, Panteleev M, Makhoul S, Gambaryan S, Jurk K / Curcumin at Low Doses Potentiates and at High Doses Inhibits ABT-737-Induced Platelet Apoptosis / Int. J. Mol. Sci. 2021 22(10) : 5405
DOI
Rukoyatkina N, Shpakova V, Panteleev M, Kharazova A, Gambaryan S, Geiger J / Multifaceted effects of arachidonic acid and interaction with cyclic nucleotides in human platelets / Thromb Res 2018 171 : 22-30
DOI

Job and position: