Gambaryan S

Gambaryan S

Gambaryan

Stepan P.

PhD

ResearcherID:  I-3940-2016
Research Gate:  Stepan_Gambaryan
Scopus ID:  7003614526
eLibrary ID:  294652

Stepan Gambaryan earned his Dr Sc in biology (physiology) in 1991 in Institute of Evolutionary Physiology and Biochemistry RAS. In 1994 he joined the Institute of Clinical Biochemistry of Wuerzburg University (Germany). In 2014 he was invited as visiting professor at the Center for Thrombosis and Hemostasis (CTH) at the Mainz University Medical Center (Germany). His main domains of research of the last 5 years include mechanisms of platelets death regulation under anticancer therapy, mechanisms of NO-cGMP system effects on platelets inhibition, mechanisms of ammonia/ammonium transport in human erythrocytes, evolution of osmotic volume regulation mechanisms in vertebrates. S.G. projects are supported by the Russian Fund for Basic Researches (contests: A, KOMFI). He is a full professor at Saint Petersburg State University Biological Faculty and has supervised a number of Master’s and PhD’ theses in Russia and abroad. Most of S.G. papers are published in such journals as Nature, Blood, Nature Methods, Journal of Thrombosis and Haemostasis, Thrombosis Haemostasis, Journal of Biological Chemistry, British Journal of Hematology, Cell Death and Disease, Cell Communication and Signaling etc

Articles

Mikhailova D, Sudnitsyna J, Kovgan P, Naida L, Kharazova A, Mindukshev I, Gambaryan S / Analysis of Ferric Protoporphyrin IX Effects on Human Platelets: Hematin Is a More Potent Agonist than Hemin / Cells 2025 14(4) : 255
DOIPubMed
Gerda B, Volkova A, Dobrylko I, Andreeva A, Dandekar T, Panteleev MA, Gambaryan S, Mindukshev I / Experimental and Mathematical Model of Platelet Hemostasis Kinetics / Cells 2025 14(9) : 677
DOIPubMed
Rukoyatkina N, Sokolova T, Pronin N, Andrei Whaley, Anastasiia OWhaley, Gambaryan S / Death of Leukemia Cells and Platelets Induced by 3,3′-Dihydroxy-4,5-Dimethoxybibenzyl Is Mediated by p38 Mitogen-Activated Protein Kinase Pathway / Molecules 2025 30(14) : 2965
DOIPubMed
Pronin N, Whaley AK, Whaley AO, Kuzmina SA, Rukoyatkina N, Gambaryan S / ISOLATION OF SECONDARY METABOLITES OF Rhaponticum carthamoides (WILLD.) ILJIN AND ASSESSMENT OF THEIR ANTIPLATELET ACTIVITY / Pharm Chem J+ 2025 59(3) : 324-329
DOIeLibrary
Jiangguo Lin, Kirill Butov, Anastasia NSveshnikova, Gambaryan S, Mikhail APanteleev / Surface-dependent reactions in blood coagulation and fibrinolysis: beyond procoagulant platelets / Biophysical Reviews 2025 17(5) : 1543-1556
DOIPubMed
Andreeva A, Chelebieva E, Mindukshev I, Gambaryan S / Effects of Stress Hormone Epinephrine and Activation of Protein Kinase A on the Osmotic Stability and Functional Parameters of Red Blood Cells From Marsh Frog / Journal of Experimental Zoology Part A: Ecological and Integrative Physiology 2025 : 1-11
DOIPubMed
Svidelskaya GS, Bruskova EN, Ignatova AA, Filkova AA, Zharkov PA, Mindukshev I, Gambaryan S, Panteleev MA / Study of Collagen-indused platelet aggregation using the method of low angle light scattering / Mosc U Phys B+ 2025 80(2) : 330-339
DOIPubMed
Fock E, Pronin N, Rukoyatkina N, Whaley A, Gambaryan S, Whaley A. / Thrombin-induced platelet inhibition by 2',4'-dihydroxychalcone and 2',4'-dihydroxydihydrochalcone is mediated by inhibition of ROS production and Thromboxane synthase a activity: structure-activity relationship of polyphenol secondary metabolites from Empetrum nigrum / Nat Prod Res. 2025 39(12) : 3382-3390
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Rukoyatkina N, Mindukshev I, Mikhailova D, Panteleev MA, Gambaryan S / Multifaceted effects of thymoquinone on platelet calcium homeostasis / Cells 2025 14(22) : 1827
DOIPubMed
Fock E, Pronin N, Rukoyatkina N, Whaley A, Gambaryan S, Whaley A / Thrombin-induced platelet inhibition by 2',4'-dihydroxychalcone and 2',4'-dihydroxydihydrochalcone is mediated by inhibition of ROS production and Thromboxane synthase a activity: structure-activity relationship of polyphenol secondary metabolites from Empetrum nigrum. / A.Nat Prod Res. 2024 3 : 1-9
DOIPubMed
Gambaryan S, Mohagaonkar S, Nikolaev V / Regulation of the renin-angiotensin-aldosterone system by cyclic nucleotides and phosphodiesterases / Front Endocrinol 2023 14 : 1239492
DOIPubMed
Gambaryan S / The Role of NO/sGC/cGMP/PKG Signaling Pathway in Regulation of Platelet Function / Cells 2022 11(4) : 3704
DOIPubMed
Mindukshev I, Fock E, Dobrylko I, Sudnitsyna J, Gambaryan S, Panteleev M / Platelet Hemostasis Reactions at Different Temperatures Correlate with Intracellular Calcium Concentration / International Journal of Molecular Sciences 2022 110(18) : 925-286-10667
DOI
Tsikas В, Gambaryan S / Nitrous anhydrase activity of carbonic anhydrase II: cysteine is required for nitric oxide (NO) dependent phosphorylation of VASP in human platelets / J Enzym Inhib Med Ch 2021 36(1) : 525-534
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Shevchuk O, JurakBegonja A, Gambaryan S, Totzeck M, Rassaf T, BHuber T, Greinacher A / Proteomics: A Tool to Study Platelet Function / Int. J. Mol. Sci 2021 22(9) : 4776
DOIPubMed
Shpakova V, Rukoyatkina N, Walter U, Gambaryan S / Potential and limitations of PKA/ PKG inhibitors for platelet studies / Platelets 2021 33(6) : 1-10
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Rukoyatkina N, Shpakova V, Bogoutdinova A, Kharazova A, Mindukshev I, Gambaryan S / Curcumin by activation of adenosine A2A receptor stimulates protein kinase A and potentiates inhibitory effect of cangrelor on platelets / Biochemical and Biophysical Research Communications 2021 586(2022) : 20-24
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Rukoyatkina N, Shpakova V, Sudnitsyna J, Panteleev M, Makhoul S, Gambaryan S, Jurk K / Curcumin at Low Doses Potentiates and at High Doses Inhibits ABT-737-Induced Platelet Apoptosis / Int. J. Mol. Sci. 2021 22(10) : 5405
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Mindukshev I, Sudnitsyna J, Goncharov N, Skverchiskaya E, Dobrylko I, Nikitina E, Кривченко А.И., Gambaryan S / Low-Dose Ammonium Preconditioning Enhances Endurance in Submaximal Physical Exercises / Sports 2021 9(2 : 1-13
Sudnitsyna J, Skverchiskaya E, Dobrylko I, Nikitina E, Gambaryan S, Mindukshev I / Microvesicle Formation Induced by Oxidative Stress in Human Erythrocytes / Antioxidants 2020 12(10) : 555-929
DOI
Fock E, Gambaryan S, Parnova R, Mindukshev I / Evaluation of the effect of e.coli lipopolysaccharide on platelets aggregation by the technique based on the registration of low angle light scattering / Ross Fiziol Zh Im I M Sechenova (Russian J Physiology) 2018 104 (7) : 835-844
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Andreeva A, Soldatov A, Skverchiskaya E, Gambaryan S, Mindukshev I / Hypoxia inhibits the regulatory volume decrease in red blood cells of common frog (Rana temporaria) / Comparative Biochemistry and Physiology. Part A: Molecular & Integrative Physiology 2018 219-220 : 44-47
DOIPubMed
Rukoyatkina N, Shpakova V, Panteleev M, Kharazova A, Gambaryan S, Geiger J / Multifaceted effects of arachidonic acid and interaction with cyclic nucleotides in human platelets / Thromb Res 2018 171 : 22-30
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