Chmykhova N
Chmykhova
Nadezhda M.
PhD
The area of scientific interest includes the structural and functional characteristics of the connections between vertebral neurons. We have shown the involvement of presynaptic group III hGluRs in the regulation of glycinergic synaptic transmission, the participation of metabotropic glutamate glutamate receptors in mGluRII both in pre- and postsynaptic modulation of the induced activity of spinal motor neurons. We evaluated the presynaptic inhibitory effect of the serotonin transmission agonist (5-CT) on the miniature inhibitory synaptic activity of motoneurons. To confirm the obtained electrophysiological data, an immunofluorescence study of the localization of receptors involved in modulation of motoneurons activity is conducted in parallel.
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