Kuznetsova L

Kuznetsova L


Ludmila A

Dr. of Biology

ResearcherID:  AAD-6596-2022
Research Gate:  Ludmila-Kuznetsova-3
Scopus ID:  7203006089
eLibrary ID:  83182

The involvement of the L-arginine-NO-synthase-NO signaling cascade in the pathogenesis of obesity, metabolic syndrome (MS), type 2 diabetes mellitus (DM2), cardiovascular diseases (CVD) and Covid-19 is considered.

Data on types of obesity, adipokine production by adipose tissue with diabetogenic (leptin, visfatin, kemerin, vaspin, apelin, resistin) and antidiabetic (adiponectin, omentin) properties are analyzed, and the role of adipokines in the development of MS and DM2 is also discussed.

The role of endothelial NO-synthase (eNOS) and nitric oxide (NO), in the pathogenesis of Covid-19 (SARS–CoV-1 virus) complicated by MS is discussed.

There is an interest in the study of neuronal nNOS, since there is a violation of its functions in the brain, myocardium, skeletal muscles can serve as evidence of violations in the pathogenesis of MS, CVD and some nervous diseases.

Section is in progress